GHK-Cu is a bioactive complex formed by the tripeptide GHK bound to copper (II). It is a molecule naturally present in the body, known for supporting cellular renewal, tissue repair, and skin integrity. With age, its levels tend to decline, which has driven its use in advanced aesthetic and regenerative protocols.
Key Benefits
Firmer, more elastic, denser skin, with a more “filled” and healthy appearance.
Improved texture and radiance, with softening of fine lines and a more even look.
Support for skin repair and recovery, helping maintain cutaneous integrity after external stressors.
Cellular protection, helping regulate inflammatory processes and the impact of oxidative stress.
Overall improved skin quality, supporting a revitalised and rejuvenated appearance throughout the protocol.
GHK-Cu is a bioactive complex formed by the tripeptide GHK bound to copper (II). It is a molecule naturally present in the body, known for supporting cellular renewal, tissue repair, and skin integrity. With age, its levels tend to decline, which has driven its use in advanced aesthetic and regenerative protocols.
Key Benefits
Firmer, more elastic, denser skin, with a more “filled” and healthy appearance.
Improved texture and radiance, with softening of fine lines and a more even look.
Support for skin repair and recovery, helping maintain cutaneous integrity after external stressors.
Cellular protection, helping regulate inflammatory processes and the impact of oxidative stress.
Overall improved skin quality, supporting a revitalised and rejuvenated appearance throughout the protocol.
Technical Details
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RECONSTITUTION, DOSING AND STORAGE OF PEPTIDES IN A VIAL
(General guidance – not peptide-specific)
1. INTRODUCTION
Peptides supplied in a vial (a glass vial containing lyophilised powder) are not ready for immediate use.
Before administration, it is mandatory to carry out reconstitution, which is the process of converting the lyophilised powder into a sterile liquid solution.
Correct reconstitution is essential to ensure:
Safe use
Peptide stability
Accurate dosing
Protocol effectiveness
⚠️ Incorrect preparation may result in inaccurate dosing and reduced effectiveness.
2. REQUIRED MATERIALS
Vial containing the lyophilised peptide
Bacteriostatic Water
Contains approximately 0.9% benzyl alcohol
Helps inhibit bacterial growth
Insulin syringe (100 units = 1 mL)
Sterile needle
Clean, hygienic environment
3. WHAT RECONSTITUTION IS
Reconstitution is the controlled addition of bacteriostatic water to the lyophilised powder, creating a liquid solution suitable for subcutaneous use.
4. GENERAL RULE FOR CALCULATING CONCENTRATION
Basic formula:
Amount of peptide (mg) ÷ Volume of water (mL) = Concentration (mg/mL)
This concentration is used to calculate the correct dose in the syringe.
5. CORRECT RECONSTITUTION TECHNIQUE
⚠️ IMPORTANT: PEPTIDES ARE FRAGILE MOLECULES
Recommended procedure:
Gently roll the vial between your fingers until fully dissolved.
**Vigorous shaking may cause peptide degradation.
6. CONVERSION FOR AN INSULIN SYRINGE
1 mL = 100 units
The amount of peptide per unit depends on the final concentration after reconstitution.
Always calculate dosing based on the concentration (mg/mL).
7. STORAGE AFTER RECONSTITUTION
Keep refrigerated between 2°C and 8°C
Do not freeze
Keep the vial tightly sealed
Protect from light, especially for photosensitive peptides
8. FINAL CONSIDERATIONS
Retatrutide is a triple agonist of GLP-1, GIP, and glucagon. This combination works in an integrated manner to reduce appetite and increase satiety, improve glycaemic homeostasis, and promote greater energy expenditure/thermogenesis via activity at the glucagon receptor.
This product is supplied as a pack of 4 vials, each containing 10 mg.
Key Benefits
Marked reduction in body weight in clinical studies, with high-impact results in obesity.
Improved glycaemic control and cardiometabolic markers (e.g., inflammatory lipids and blood pressure reported in readouts).
Reduced liver fat and improvements associated with metabolic liver disease (MASLD/MASH) in a Phase 2a study.
Quality of weight loss (body composition): evidence suggests a greater reduction in fat mass, without a disproportionate increase in lean mass loss, in body-composition sub-studies.
Tirzepatide is a dual agonist of GIP and GLP-1 receptors, acting in an integrated way across incretin pathways. It increases insulin secretion in a glucose-dependent manner and improves glycaemic regulation (reducing peaks and variability). It also acts on appetite/satiety centres, contributing to reduced food intake.
This product is supplied as a pack of 4 vials, each containing 15 mg.
Key Benefits
Significant reduction in body weight in studies involving people with obesity/overweight (results depend on dose, duration, and adherence).
Robust improvement in glycaemic control (HbA1c) in people with type 2 diabetes, with dose-dependent reductions observed in clinical trials.
Cardiometabolic improvements associated with weight loss and incretin pathway activity.
Maintenance of weight loss with continued treatment, demonstrating sustained outcomes when use is maintained within protocol (in maintenance trials).
Intelligent metabolic regulation for consistent weight loss.
Tirzepatide is a dual agonist of GIP and GLP-1 receptors, acting in an integrated way across incretin pathways.It increases insulin secretion in a glucose-dependent manner and improves glycaemic regulation (reducing peaks and variability).
It acts on appetite/satiety centres, helping to reduce food intake and supporting adherence to body recomposition strategies.
Key Benefits
Mechanism of Action
Retatrutide is a triple agonist of GLP-1, GIP, and glucagon receptors. This combination works in an integrated manner to reduce appetite and increase satiety, improve glycaemic homeostasis, and promote greater energy expenditure/thermogenesis via activity at the glucagon receptor.
Key Benefits
– Marked reduction in body weight in clinical studies, with high-impact results in obesity.
– Improved glycaemic control and cardiometabolic markers (e.g., inflammatory lipids and blood pressure reported in readouts).
– Reduction in liver fat and improvements associated with metabolic liver disease (MASLD/MASH) in a Phase 2a study.
– Quality of weight loss (body composition): evidence suggests a greater reduction in fat mass, without a disproportionate increase in lean mass loss, in body-composition sub-studies.
– Tolerability profile consistent with the incretin class, with gastrointestinal events most commonly reported in studies (e.g., nausea, diarrhoea, and constipation).