A synthetic peptide composed of four amino acids (Ala–Glu–Asp–Gly). It “resets” the cellular biological clock and synchronises the pineal gland to restore the circadian cycle and the rhythmic secretion of melatonin. It is used in protocols focused on systemic rejuvenation, the management of sleep disorders and jet lag, immune system support in older adults, and the prevention of cognitive decline. Key Benefits Telomere extension: by activating telomerase, it may allow cells to divide for longer, helping to counter cellular senescence. Circadian rhythm regulation: supports natural melatonin production by the pineal gland, resulting in better sleep quality. Antioxidant action: reduces lipid oxidation and helps counter free radicals. Metabolic health: studies suggest improvements in insulin sensitivity and lipid profile. Prevention of age-related diseases: potential to reduce the incidence of tumours and neurodegenerative diseases.